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Graphical presentation of CX-5461-mediated activation of the cytosolic DNA sensing pathway. cGAS binding on the cytosolic DNA activates the secondary messenger two,3-cGAMP applying cGAS like a catalyst. Activated STING buds from the ER moving for the perinuclear Golgi, wherever it is palmitoylated.Numerous sorts of pores and skin bacterial infectio
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